| | LA Galaxy @ | San Jose Earthquakes | Saturday, June 25, 2022 | 7:30p |
| | Montreal @ | Seattle Sounders | Wednesday, June 29, 2022 | 7:00p |
| | Atlanta Caffeine & Octane 1 | Atlanta, GA | Sunday, July 3, 2022 | |
| | La Galaxy @ | LAFC | Friday, July 8, 2022 | 7:00p |
| | San Jose @ | LA Galaxy | Wednesday, July 13, 2022 | 7:00p |
| | Philadelphia @ | Orlando City SC | Saturday, July 23, 2022 | 7:30p |
| | Portland @ | Minnesota United FC | Saturday, July 30, 2022 | 2:00p |
| | Seattle @ | Atlanta United | Saturday, August 6, 2022 | 3:00p |
| | Atlanta Caffeine & Octane 2 | Atlanta, GA | Sunday, August 7, 2022 | |
| | MLS All Star @ | St. Paul, MN | Wednesday, August 10, 2022 | 7:00p |
| | Atlanta @ | FC Cincinnati | Saturday, August 13, 2022 | 6:30p |
| | Dallas @ | Nashville SC | Sunday, August 21, 2022 | 7:30p |
| | Columbus @ | FC Cincinnati | Saturday, August, 21, 2022 | 7:30p |
| | Chicago @ | New England Revolution | Wednesday, August 31, 2022 | 7:30p |
| | Charlotte Cars and Coffee | Charlotte, NC | Saturday, September 3, 2022 | |
| | Orlando @ | Inter Miami | Sunday, Saturday 4, 2022 | 7:00p |
| | Philadelphia @ | Nashville SC | Saturday, September 10, 2022 | 3:30p |
| | Miami @ | Chicago Fire FC | Saturday, September 10, 2022 | 7:00p |
| | LAFC @ | Minnesota United FC | Tuesday, September 13, 2022 | 7:00p |
| | Charlotte FC @ | Chicago Fire FC | Saturday, September 17, 2022 | 7:00p |
| | Philadelphia @ | Charlotte FC | Saturday, October 1, 2022 | 7:00p |
| | Jacksonville Caffeine & Octane 1 | Jacksonville, FL | Saturday, October 8, 2022 | |
| | Columbus @ | Orlando City SC | Sunday, October 9, 2022 | 7:30p |
| | Miami Auto Show | Miami, FL | Friday, October 14, 2022 | |
| | MLS Playoff Game 1 | TBD | Saturday, October 15, 2022 | TBA |
| | MLS Playoff Game 2 | TBD | Thursday, October 20, 2022 | TBA |
| | Miami Auto Show | Miami, FL | Thursday, October 20, 2022 | |
| | MLS Playoff Game 3 | TBA | Tuesday, October 25, 2022 | TBA |
| | MLS Cup | TBA | Saturday, November 5, 2022 | TBA |
| | Los Angeles Auto Show | Los Angeles, CA | Friday, November 18, 2022 | |
| | Los Angeles Auto Show | Los Angeles, CA | Thursday, November 24, 2022 | |
| | Central Florida Auto Show | Orlando, FL | Friday, December 2, 2022 | |
| | San Diego Auto Show | San Dieo, CA | Thursday, December 29, 2022 | |
